Tuesday, June 10, 2014

Day Minus Six

            David is back at MGH, in Lunder room 1034, preparing for his stem cell transplant. (“Bone marrow transplant” and “stem cell transplant” are often used interchangeably, but David will receive Sam’s stem cells into his bloodstream. These stem cells will migrate to David’s bone marrow over the following weeks.)

            In the transplant schedule, the day of transplant is designated “day zero”. Today, “day minus six”, his chemotherapy started around 4:30 p.m. For four consecutive days he will receive Fludarabine by IV approximately one hour a day and Busulfan by IV, two hours a day.

            In about two days he will start taking Tacrolimus, an immunosuppressive drug, to reduce the risk of graft-versus-host disease (GVHD). Sam’s stem cells are the “graft”, David’s body is the “host”. There is a risk that the transplanted stem cells will attack David’s liver, skin, and/or gastro-intestinal tract.

            On Thursday, “day minus four”, Sam will start receiving injections to increase the number of stem cells and encourage them to migrate into his bloodstream. On Monday, June 16th, ‘day zero”, Sam will be attached to a machine for several hours, which will collect stem cells from his bloodstream and then return the rest of his blood back into a vein. If all goes well, David will receive these stem cells that same day.

            The right end of the couch in room 1034 has a great view of Beacon Hill and the Statehouse. We lost the view of the Charles River we enjoyed in room 1040.

            David’s in good spirits. He finished Season Three of Avatar today. For our annual Family Holiday last Thursday, Jim, David, Sam, and I watched several episodes, plus a Doc Martin.

            According to the “Transplant Schedule” Dr. Chen gave us, day minus six to day plus one are marked, “boring”. We hope so.

2 comments:

  1. Thank you for the updates. I do read them and I also try not to "hover". David remains in our prayers, and of course there is more broth frozen here and fresh juice or soups when they would again be helpful. I loved hearing about R'el's concert.

    ReplyDelete
  2. Thanks so much for the update. I have been at Jeff's since a week ago Wednesday and am going to Shelley tomorrow. Sam, you are a trouper. We are very grateful that your blood is a good match. You are all in my thoughts and prayers. Love, Meemaw

    ReplyDelete